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Our society is facing an opioid crisis.

But together we can defeat it.


Resources for an Evolving Crisis: Preventing Overdose from Combined Substances

Resources to help health and human services providers, people with SUD and their families and friends, local leaders, and others respond to risks related to polysubstance use.

Ecosystem of Recovery

An approach to create broader access to and community-wide support for best practices in opioid use disorder treatment.

Suicide Prevention Training

SafeSide Prevention has developed evidence-based workforce education to address suicide risk related to opioid use disorder in rural communities.

Engaging Patients into Care upon Release from Incarceration

Transitions Clinic Network programs address the high rates of overdose mortality among individuals recently released from incarceration and other health risks and challenges these patients face.

Removing Barriers on the Road to Recovery

The ROADSS program brings lifesaving treatment closer to home in rural communities.



Technical Assistance Center

We are working with specific counties in the Appalachian regions of Kentucky, New York, Ohio, and West Virginia as they apply evidence-based practices to fight the opioid crisis, especially related to synthetic opioids.

We also support communities across the U.S. as they find, adapt, and implement programs.

We look forward to connecting with you!

News & Events


Webinars & more


Our newsletter, Turning Pages, highlights best practices and rural health resources.

Overcoming Barriers to Treatment and Recovery

Supporting Recovery in Northern Appalachia

Teamwork to Reduce Stigma

Staff Wellness during COVID-19


COVID-19 has put a new obstacle in our path as we fight the opioid crisis. But we are adapting to this challenge and moving forward.

Learn more